Stalosan® F

The Avian Influenza virus strain H9N9 has been seen more often and keep spreading

The Avian Influenza (AI) virus strain H9N9 has been seen more often and keeps spreading. The University of Minnesota conducted a research trying to determine the Stalosan F efficacy against this particular virus. The product has been tested already against highly pathogenic avian influenza virus H5N1 and the study indicated excellent results.

This research performed by UM is the second test demonstrating that Stalosan F is effective against one more type of AI virus - H9N9.

Stalosan product manager, DVM Ivan Gospodinov explains:  “Speaking from a biosecurity standpoint Stalosan F is the only product in this category with documented efficacy against two different AI viruses - H5N1 and H9N9. As a manufacturer of this product, we are proud to announce the second test and the excellent results that Stalosan F achieved.’’

The test conducted in association with University of Minnesota was performed in triplicate and with four different contact times - between 5 minutes and 6 hours. All four contact intervals in the triplicate study revealed almost the same efficacy of Stalosan F against the tested organism.

Ivan Gospodinov continues, “The results once again illustrated that Stalosan F stands firm in its category and why it is often imitated – but never duplicated”.

Stalosan F and the chemical balance in housings

By Jan Storgaard, Biochemist, Stormøllen

Stalosan F is known for its high concentration of active substances (>95%) providing optimal effect and protection towards a number of well-known problems and diseases in modern pig productions. For instance, a number of studies have been carried out in co-operation with research teams from e.g. Universities of Lund and Copenhagen, in which Stalosan has shown a very significant effect on e.g. E.coli, salmonella, staphylococcus and streptococcus. Even after 50 years of study, it has not been possible to find one microorganism that Stalosan F cannot control.

 

The influence of the pH-value on diseases in housings

Ammonia (pH=13) raises the pH-value in the housing environment and that is harmful to animals and strongly increases the risk of infections and diseases. Thus, studies have been conducted showing that e.g. respiratory infections, claw diseases, diseases of the alimentary tract and skin diseases are increasing significantly at a higher pH-value and ammonia level. The explanation of this phenomenon has to be found in the way animals control bacteria. On the surface of the skin a protective acid mantle (pH=4.5) is constantly produced with a high content of different fatty acids strongly inhibiting all pathogenic bacteria, because they have a low tolerance for acids. By using this simple and effective method, harmful bacteria and infections are inhibited and diseases are largely prevented, if the acid mantle is undamaged and efficient. At the same time, the acid mantle is functioning as a lubricant for the skin keeping it smooth and resistant.

The large amounts of ammonia in the housing increases the pH-value and creates an alkaline environment, which is destroying the acid mantle and neutralising the fatty acids. At the same time the skin and mucous membranes are desiccated and thus impaired, they fissure. Consequently, bacteria have easy access resulting in infection and pathogenicity.

These decisive relations between the pH-value in housings and the frequency of infections and diseases make it absolute necessary to choose a disinfectant in powder form with a low pH-value in order to compensate for the increased pH-value in the housing and to counteract the harmful after-effects.

Stalosan (pH=3.5) has a very high content of special acid minerals reducing the pH-value in the immediate environment of the pig very effectively. In this way, the pig’s own immune system is supported significantly on skin, mucous membranes/respiratory passages and stomach. 

Typical disinfectants in powder form are having a pH-value between 9 and 10 due to the high content of calcium carbonate. It is not advisable to use calcium carbonate  in housings, because it contributes to a pH raise along with ammonia, and thus destroying the acid mantle and impairing the skin and mucous membranes.

Ph Tabel

Please, see the illustration about pH-value. Look for further information on this topic at our home page: vitfoss.com

Stalosan® F delivers powerful punch to PEDv

PEDv, a viral disease to which suckling pigs and newly weaned piglets are particularly vulnerable, now looks to have a powerful opponent. Researchers at the University of Minnesota have shown that Stalosan F is particularly effective against PEDv.

 

PEDv has caused significant losses for a number of years in the United States, China and Eastern Europe. Although it is now tapering off in the US, the status remains unchanged in China and Eastern Europe. In order to evaluate the possibilities of limiting this disease on an international level, Vitfoss decided earlier this year to have researchers look at whether Stalosan F, already known for being effective against PRRS virus as well as Salmonella- and Lawsonia bacteria, has any effect against PEDv.

Results from a series of lab tests at the University of Minnesota show that Stalosan has a significant effect on PEDv.

Pedv Stalosan

“The results obtained by the researchers are extremely interesting. So it is significant that Stalosan F appears to have a particularly good effect, as it almost completely eliminated the PED virus in trials. According to the trials it is 99.9% effective,” says Ivan Gospodinov, who oversaw trial design in cooperation with the University of Minnesota, USA.

The clear messages from American researchers mean that Vitfoss is now gearing up to market Stalosan F and the product’s efficacy to prevent and fight PEDv in those areas of the world where the diseases remains a problem.

PEDv results in reduced appetite, diarrhoea and vomiting.

PEDv is a major problem in many countries, so we now want to drill down on getting the news and the product out to the affected areas and to minimise spread of the disease,” says Dr Ivan Gospodinov.


Danish veterinarian Pia Conradsen, from Svinevet, applauds the new results.

“In addition to the fact that infected herds need to be immunised, step two is then to reduce infection pressure. This is where the results from the Stalosan F tests are immensely interesting: until now we did not have any effective agents against it,” says Conradsen, who also stresses that it is important to reduce infection pressure on infected properties, just as it is critical to limit risk of spreading the infection during transport between herds.


About Stalosan F
Stalosan F was launched in 1965 and is a disinfectant with documented efficacy. It has been used in more than 50 countries for 50 years.
Vitfoss owns the rights to manufacture, market and sell Stalosan F in Denmark. It is the Vilofoss group (which like Vitfoss is part of the DLG group) that operates on the international level.
Stalosan F is a Biosecurity product that is very significant when it comes to creating good economic conditions in operations, including the prevention and treatment of PEDv.
Stalosan F, which is a disinfectant that binds ammonia and water, is effective against pathogens including Salmonella, PRRS, Lawsonia and PEDv. Generally, we see that Stalosan used in livestock helps reduce mortality, reduce dependence on medicines, increase daily growth and improve feed utilisation.
One of the many advantages of Stalosan is that it can be used in pens while the animals are present. It works within seven days on average, and there are no negative effects on the environment or on equipment.
The Stalosan specialists at Vitfoss are trained veterinarians.


Additional information:
Dr Ivan Gospodinov igo@stalosan.com, Dr Plamen Nikolov pvn@stalosan.com, Ewa Nick eni@vitfoss.dk,

Dr Seferinov Tihomir sfs@stalosan.com, Dr Chavdar Zemyarski caz@stalosan.com


Appendix:


Efficacy of Stalosan F against PEDv.

Dosage

Time after

application

Viral load

Virus reduction;
%

Control

Stalosan F

A

5 min

4.83

<1

≥ 99.99

 

10 min

4.83

<1

≥ 99.99

 

60 min

4.50

<1

≥ 99.96

 

6 hours

4.50

<1

≥ 99.96

B

5 min

4.83

<1

≥ 99.99

 

10 min

4.50

<1

≥ 99.96

 

60 min

5.17

<1

≥ 99.99

 

6 hours

4.50

<1

≥ 99.96

Results from the University of Minnesota, from professor of virology Sagar M. Goyal. August 2015.

 

Read the entire study here